[VoxBo] normalization and origins

[Katharina Spalek]

Hi,

I have a puzzling issue with the origins in my normalized anatomical.cub 
files. I have run identical preprocessing procedures for 16 subjects. 14 
out of the 16 have the origin where it should be, while the last two 
subjects in the series show it somewhere in the left superior frontal 
gyrus. (This is when I open the file in vbview and click on "show 
origin"). Now I have a couple of questions:

a) Why would this happen? Does it matter that the "diverging subjects" 
were the last subjects scanned, i.e., could there be a bug in the files 
the scanner generated?

b) I don't really know in which steps of the data analysis origin 
information is relevant, so can someone please enlighten me where 
different origin information will mess up my data?

c) At which point in the processing stream can I set the origin manually 
to make sure that the information will be correct for all subsequent 
steps? (Note that I'm not using the bigprep.vbp script, but the 
preprocessing script that is used, I believe, by everyone in Geoff's lab).

d) Should I, for starters, just re-run the preprocessing for the two 
"weird" subjects and see what happens? In an ideal world, re-running the 
identical script should not change the outcome, but ...

Many thanks for any thoughts and advice on this problem,

Katharina